Custom Synthesis

We specialize in synthesis of novel organic compounds, process development and manufacturing of pharmaceutical and fine organic chemicals from gram to kilogram quantities.

Standard Custom Synthesis

At Yuhao Chemical we are able to synthesize a large variety of molecules including

─  building blocks, scaffolds and synthons for combinatorial chemistry or further synthesis,

─  new chemical entities or analogues for lead discovery and optimization

─  reference compounds such as metabolites or impurities for process validation

Yuhao Chemical offer lab-scale custom synthesis and contract research through state-of-the-art reaction methods and techniques. We have the expertise and equipment to cover the full range of organic reactions, with an emphasis on heterocyclic chemistry, catalytic reactions, asymmetric reactions and high-pressure reactions and hydrogenations.

Scale-up Synthesis

Scaling up laboratory compound synthesis is always a difficult and costly task. Yuhao Chemical's process chemistry experts will work to shorten the synthetic procedure and substitute cheaper materials to provide the safest and most cost-effective option for production of up to 10 kg in Yuhao Chemical's kilo lab.

─  Process optimization for shorter synthesis

─  Scheme modification to use cheaper reagents

─  Kilo lab with capacity up to 10kg

─  Efficient knowledge transfer to plant

When it is time to synthesize more than 10 kilograms, you can take advantage of our large-scale synthesis specialists. All synthetic procedures are documented in detail and are efficiently transferred to our plants for large scale.

Price and Delivery Time

Price and delivery time will depend on the specific chemical structure and bibliographic study of known processes. Yuhao Chemical honors its quoted price even if a project requires more work than anticipated. We will charge the client only for successful syntheses.

Confidential Agreement

Intellectual property is the most important asset of our company as well as our clients. We will sign the confidential agreement with customers before project conduction as required. We deal with every part of our work with the highest integrity no matter how small it is within a whole development and manufacturing process. All the employees will sign the confidential agreement with us before entering the Lab. We also establish rigorous documentation system to safeguard customers’ IP including daily-signature of lab notebook and regular filing of all involved documents.

Contract Research

Yuhao Chemical provide customers with a variety of contract research options. The core service is Full Time Equivalent (FTE) based chemistry. When you are up to a project needing contract research, contract organic synthesis, R&D synthesis, our team of organic chemists will be able to achieve your goal effectively in short period of time.

The client contracts for one or more Yuhao Chemical chemists to work on its projects full-time. The client is invoiced quarterly for the contracted amount, plus project-specific raw materials.  All Intellectual Property (IP) is owned by the client. This model provides reliable capacity, since the chemist(s) is devoted to the client. It also provides maximum flexibility and efficiency, since client direction changes can be made at any time without reissuing purchase orders or revising contracts.

Delivery